|
KMID : 0613820110210071052
|
|
Journal of Life Science
2011 Volume.21 No. 7 p.1052 ~ p.1059
|
|
|
Antioxidative Activity and Chemical Characteristics of Leaves, Roots, Stems and Fruits Extracts from Acanthopanax senticosus
|
|
Heo Su-Jin
Ahn Hee-Young
Kang Min-Jung
Lee Jae-Hong
Cha Jae-Young
Cho Young-Su
|
|
|
Abstract
|
|
|
|
The contents of bioactive and antioxidative activities (DPPH (α,α’-diphenyl-β-picrylhydrazyl), free radical scavenging activity, peroxidation of linoleic acid and rat hepatocyte microsome, and Fe/Cu reducing power, tyrosinase inhibition activity) were tested by in vitro experimental models using water, hot water, ethanol and methanol extracts of leaves (ASL), roots (ASR), stems (ASS) and fruits (ASF) from Acanthopanax senticosus. Hot water extract from ASL showed the highest extraction yield (16.04%) as well as highest contents of phenolic compounds (2.67%) and flavonoids (1.43%). Major minerals were K, Ca and Mg. In oxidation in vitro models using DPPH free radical scavenging activity, Fe/Cu reducing power, Fe²?/ascorbate-induced linoleic acid peroxidation by ferric thiocyanate and thiobarbituric acid (TBA) methods, tyrosinase inhibition activity and autooxidation of rat hepatic microsomes membrane, and antioxidative activities were strong in Acanthopanax senticosus. From these results, ASL extracts were shown to have the most potent antioxidative properties and contain the highest amounts of antioxidative compounds such as phenolic compounds and flavonoids. These results may provide the basic data to understand the biological activities of bio-active materials derived from leaves of Acanthopanax senticosus.
|
|
|
KEYWORD
|
|
|
Acanthopanax senticosus, DPPH, antioxidative activity, phenolic compounds, flavonoids
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|